Keynotes on the Neuroscience of Leadership, Decision-Making, and Change

Neuroscientist • TEDx Speaker • Translating brain science into real-world decision-making under pressure

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Conferences

Executive Offsites

Senior Leadership Teams

Leadership Events

Flagship Keynote

Top-Down Leadership:

Training the Brain for Pressure, Uncertainty, and Complexity

This keynote explains why pressure reliably degrades decision-making, even in highly capable leaders, and how to intervene in real time. Drawing on neuroscience, evolutionary biology, and high-stakes performance, Dr. Devin Effinger shows how stress shifts brain control, why the nervous system prefers certainty over accuracy, and how leaders regain top-down control in complex environments.

Bullets:

  • Why smart leaders become reactive under pressure

  • How ancient survival wiring clashes with modern work

  • Why false certainty drives conflict and poor decisions

  • A practical framework leaders can use immediately

This keynote is ideal for:

  • Conferences

  • Executive offsites

  • Leadership retreats

Additional Keynote Topics

These talks share a common neuroscience foundation but are designed for different audiences and contexts.

Voluntary Evolution

Why Humans Must Learn to Override Their Own Biology

A big-picture keynote on evolutionary mismatch, modern overstimulation, and why deliberate, “contrary” action is becoming a core human skill.

Best for: innovation, future-of-work, culture, TEDx-style audiences

Why the DSM Is Failing Us — and What Neuroscience Is Pointing Toward Instead

A thought-leadership keynote reframing mental health through circuits and states rather than symptom labels, and exploring what neuroscience and psychedelics are revealing about future care models.

Best for: clinical, academic, policy, and healthcare leadership audiences

From Survival Mode to Self-Directed Change

A neuroscience-based keynote on trauma, addiction, and chronic stress as brain adaptations—not moral failure—and how agency is rebuilt through structure and top-down regulation.

Best for: treatment centers, recovery conferences, justice-involved and resilience-focused audiences

What Psychedelics Are Teaching Us About the Brain

A science-forward talk on neuroplasticity, predictive processing, and meaning-making, focused on mechanisms and integration rather than advocacy.

Best for: medical, innovation, and mental health audiences

From TEDx to the Boardroom

These keynotes build on ideas first presented in a TEDx talk, adapted for leadership, organizational, and professional audiences. While the TEDx focused on why these patterns matter, the keynotes focus on how they show up—and how to intervene in real time.

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About the Speaker

Dr. Devin Effinger is a neuroscientist and TEDx speaker who studies how stress, uncertainty, and prediction shape human behavior. His work focuses on the neurobiology of decision-making under pressure and the mismatch between ancient survival wiring and modern organizational demands. Devin’s talks are evidence-based, non-therapeutic, and designed for leaders operating in complex, high-stakes environments.

  • "Incredibly power speaker, blending science and lived experience"

    Former Customer

  • "Someone who is an expert in neuroscience, but who also has the street smarts to understand practical application"

    Former Customer

  • "A rare talk in that it was powerful but left me with tools I didn't have before"

    Former Customer

Book Dr. Devin for Your Event

Available for conferences, executive offsites, and leadership retreats.